منابع مشابه
The Kinetics of Enzyme Mixtures
Even purified enzyme preparations are often heterogeneous. For example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. For this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. Based...
متن کاملImplications of enzyme kinetics.
Of the many examples of oscillatory kinetic behaviour known, several are briefly reviewed, including those of glycolysis, the peroxidase-oxidase reaction and oscillations in cellular calcium concentration. It is shown that simple mathematical models employing allosteric rate laws are sufficient to explain the instability of the steady state and the appearance of sustained oscillations. The cAMP...
متن کاملEnzyme kinetics at high enzyme concentration.
We re-visit previous analyses of the classical Michaelis-Menten substrate-enzyme reaction and, with the aid of the reverse quasi-steady-state assumption, we challenge the approximation d[C]/dt approximately 0 for the basic enzyme reaction at high enzyme concentration. For the first time, an approximate solution for the concentrations of the reactants uniformly valid in time is reported. Numeric...
متن کاملthe kinetics of enzyme mixtures
even purified enzyme preparations are often heterogeneous. for example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. for this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. based...
متن کاملThe Kinetics of Multiple Enzyme
In the course of studies on the adaptive fermentation of galaetose by yeast, the effects of a number of enzyme inhibitors on the adaptive process and the subsequent fermentation were investigated. The results of these experiments as they bear on the problem of adaptation have been discussed in a preliminary communication (1). However, one interesting point emerged in concentration curves fgr tw...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1972
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(72)86084-3